Table 1.
Complexes and functional groups of translation-associated proteins classified according to functional and physical interactions.
| Complex or Group | Protein Names |
|---|---|
| eIF2 | EIF2S1, EIF2S2, EIF2S3 |
| eIF2B | EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5 |
| eIF3 | EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3J, EIF3K, EIF3L, EIF3M |
| Multifactor complex (MFC) | EIF1, EIF1AX, EIF1AY, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3J, EIF3K, EIF3L, EIF3M, EIF5 |
| eIF4s | EIF4A1, EIF4A2, EIF4B, EIF4H, EIF4E, EIF4E1B, EIF4E3, EIF4G1, EIF4G3 |
| eIF4, 4EBP | EIF4EBP1, EIF4EBP2, EIF4EBP3, EIF4A1, EIF4A2, EIF4B, EIF4H, EIF4E, EIF4E1B, EIF4E3, EIF4G1, EIF4G3 |
| INITIATION | EIF1, EIF1AX, EIF1AY, EIF1B, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3J, EIF3K, EIF3L, EIF3M, EIF4A1, EIF4A2, EIF4B, EIF4H, EIF4E, EIF4E1B, EIF4E3, EIF4G1, EIF4G3, DDX3X, DDX3Y, DHX29, EIF4EBP1, EIF4EBP2, EIF4EBP3, EIF5, EIF5B, PABPC1 |
| INITIATION+ | EIF1, EIF1AX, EIF1AY, EIF1B, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EIF2S1, EIF2S2, EIF2S3, EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3J, EIF3K, EIF3L, EIF3M, EIF4A1, EIF4A2, EIF4B, EIF4H, EIF4E, EIF4E1B, EIF4E3, EIF4G1, EIF4G3, DDX3X, DDX3Y, DHX29, EIF4EBP1, EIF4EBP2, EIF4EBP3, EIF5, EIF5B, EIF6, PABPC1, ABCE1, EIF2D, MCTS1, DENR, MCTS2P, BZW1, BZW2, EIF4E2, EIF4G2, CTIF, PAIP1, PAIP2, EIF2A, ABCF1, NCBP1, NCBP2 |
| eEF1B | EEF1B2, EEF1D, EEF1G |
| eEF1H | EEF1A1, EEF1A2, EEF1B2, EEF1D, EEF1G, VARS1 |
| ELONGATION | EEF1A1, EEF1A2, EEF1B2, EEF1B2P2, EEF1D, EEF1G, EEF2, EEFSEC, EIF5A, EIF5A2 |
| ELONGATION+ | EEF1A1, EEF1A2, EEF1B2, EEF1B2P2, EEF1D, EEF1G, EEF2, DPH1, DPH2, DPH3, DPH5, DPH6, DPH7, EEFSEC, EIF5A, EIF5A2, EIF5AL1, DHPS, DOHH |
| ELONGATION+ GTPBPs |
GTPBP1, GTPBP2, EEF1A1, EEF1A2, EEF1B2, EEF1B2P2, EEF1D, EEF1G, EEF2, DPH1, DPH2, DPH3, DPH5, DPH6, DPH7, EEFSEC, EIF5A, EIF5A2, EIF5AL1, DHPS, DOHH |
| TERMINATION | ETF1, GSPT1, GSPT2 |
| TERMINATION+ | ETF1, GSPT1, GSPT2, PABPC1, ABCE1, EIF2D, MCTS1, DENR, MCTS2P, HBS1L, PELO |
| PABPC paralogs | PABPC1L, PABPC1L2A, PABPC1L2B, PABPC3, PABPC4, PABPC4L, PABPC5, PABPC1 |
| ARSases | AIMP1, AIMP2, EEF1E1, NARS, RARS, EPRS, MARS, QARS, IARS, KARS, LARS, YARS, VARS, AARS, CARS, DARS, FARSA, FARSB, GARS, HARS, HARS2, SARS, SARS2, TARS, TARSL2, WARS, LARS2, RARS2, VARS2, AARS2, TARS2, YARS2, WARS2, NARS2, PARS2, MARS2, IARS2, FARS2, EARS2, DARS2, CARS2 |
| ARSase COMPLEX | AIMP1, AIMP2, EEF1E1, NARS, RARS, EPRS, MARS, QARS, IARS, KARS, LARS |