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Molecular docking of (−)-dendroparishiol and reference compounds on COX-2 and iNOS. (A,B) Overlay binding mode of (−)-dendroparishiol and rofecoxib on COX-2. (C,D) Two-dimensional binding mode showing the interaction of (−)-dendroparishiol (C) and rofecoxib with COX-2. (E,F) Overlay binding mode of (−)-dendroparishiol and AR-C95791 on iNOS. (G,H) Two-dimensional binding mode showing the interaction of (−)-dendroparishiol (G) and AR-C95791 (H) with iNOS.
