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Effect of RGE on ovarian senescence in mice with POF. p16 immunofluorescence staining (a); Expression of p53, p21, p16, and klotho proteins was analyzed by western blotting with specific primary antibodies (b–f). Data are expressed as Mean ± SD (n = 15). ** p < 0.01 vs. normal group; ## p < 0.01 vs. D-gal group.
