Figure 5.

Histological analysis of liver tissue of mice after HFD feeding, oral P. gingivalis (Pg) inoculation, and imipramine treatment. C57BL/6 mice were fed HFD to induce MetS/NAFLD and orally inoculated with Pg to induce periodontitis. Part of the mice were also treated with imipramine. At the end of the study, the livers of the mice were dissected, sectioned, and stained with hematoxylin and eosin for histological analysis. Representative images of liver sections in eight groups were shown, and the images in the insets were enlarged. Scale bar = 100 μm.