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. 2023 Apr 30;24(9):8101. doi: 10.3390/ijms24098101

Figure 2.

Figure 2

Figure 2

The ITK inhibitor downregulated Th17-related signaling in the periphery of sepsis survivor mice. (A) Representative flow plot for IL-17A+ CD4+ T cells’ immunostaining; (B) Representative flow plot for p-STAT3+ CD4+ T cells’ immunostaining; (C) Representative flow plot for p-NFkB+ CD4+ T cells; (D) % of IL-17A+ CD4+ T cells; (E) % of p-STAT3+ CD4+ T cells; (F) % of p-NFkB+ CD4+ T cells; and (G) IL-17A protein levels in serum. The values are depicted as the mean ± SEM, n = 6/group. *** p < 0.001; **** p < 0.0001.