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ITK inhibitor caused a reduction in IL-17A-related signaling in the CNS of sepsis survivor mice. (A) IL-17A mRNA expression; (B) IL-17A protein levels; and (C) p-NFkB protein levels. The values are depicted as the mean ± SEM, n = 6–8/group. ** p < 0.01; *** p < 0.001; **** p < 0.0001.
