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ITK inhibitor caused a reduction in oxidative and inflammatory mediators in the CNS of sepsis survivor mice. (A) MPO activity; (B) iNOS mRNA expression; (C) Lipid peroxides; (D) IL-6 mRNA expression; and (E) MCP-1 mRNA expression. The values are depicted as the mean ± SEM, n = 6–8/group. ** p < 0.01; *** p < 0.001; **** p < 0.0001.
