Table 3.
Univariate and multivariate analysis for patients with AF and COPD on BB therapy.
| All-Cause Mortality | Cardiovascular Mortality | Hospitalizations | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate Analysis | Multivariate Analysis |
Univariate Analysis |
Multivariate Analysis |
Univariate Analysis |
Multivariate Analysis | |||||||
| HR (95% CI) | p-Value | aHR (95% CI) | p-Value | HR (95% CI) | p-Value | aHR (95% CI) | p-Value | HR (95% CI) | p-Value | aHR (95% CI) | p-Value | |
| Diabetes mellitus | 1.16 (0.70, 1.94) |
0.57 | 109 (0.63, 1.88) |
0.76 | 1.20 (0.67, 2.17) |
0.53 | 1.17 (0.64, 2.15) |
0.6 | 1.16 (0.66, 2.03) |
0.6 | 1.41 (0.77, 2.58) |
0.26 |
| LVEF ≤ 40% | 2.88 (1.68, 4.94) |
<0.01 | 2.85 (1.51, 5.36) |
<0.01 | 3.34 (1.84, 6.07) |
<0.01 | 3.20 (1.59, 6.44) |
<0.01 | 1.69 (0.90, 3.16) |
0.1 | 1.03 (0.47, 2.28) |
0.94 |
| Age | 1.04 (1.01, 1.07) |
0.02 | 1.05 (1.01, 1.08) |
0.02 | 1.04 (1.00, 1.07) |
0.05 | 1.04 (1.00, 1.08) |
0.05 | 1.04 (1.00, 1.07) |
0.05 | 1.04 (1.00, 1.08) |
0.05 |
| CAD | 155 (0.91, 2.62) |
0.1 | 1.04 (0.55, 1.97) |
0.9 | 1.75 (0.97, 3.16) |
0.06 | 1.20 (0.58, 2.43) |
0.61 | 1.21 (0.70, 2.10) |
0.49 | 1.27 (0.62, 2.62) |
0.51 |
| Cardioselective BB | 0.93 (0.55, 1.57) |
0.78 | 1.10 (0.63, 1.94) |
0.73 | 1.06 (0.59, 1.9) |
0.85 | 1.33 (0.71, 2.51) |
0.37 | 0.99 (0.55, 1.79) |
0.98 | 1.65 (0.80, 3.38) |
0.17 |
| Prior stroke | n.s. | n/a | n.s. | n/a | 0.71 (0.35, 1.47) |
0.36 | 0.79 (0.36, 1.77) |
0.56 | ||||
(a) HR: (adjusted) hazard ratio, CI: confidence intervals, n.s.: non-significant, and n.a.: not applicable. p-values marked in bold indicate statistically significant tests (p < 0.05).