Table 3.
BPA levels found in samples of human adipose tissue.
| References (Year) | Type of Participants (n: Number of Participants) | Levels Found (ng/g Tissue) |
Detection Method | Country |
|---|---|---|---|---|
| Venisse et al. (2019) [68] | Patients during breast or prostate surgery (n: 5). | Range: 1.19–8.73. | LC-MS/MS | France |
| Artacho-Cordón et al. (2017) [64] | Patients undergoing trauma surgery (n: 14). | Mean: 0.60. | HPLC | Spain |
| Reeves et al. (2018) [69] | - Breast cancer mastectomy patients: (n: 36); - Control group: reduction mammoplasty patients (n: 14). |
Mean (SD): - Breast cancer mastectomy patients: - Among all samples 0.19 (0.35); - Among samples with detectable BPA 0.71 (0.31); - Control: - Among all samples 0.26 (0.37); - Among samples with detectable BPA 0.66 (0.27). |
HPLC-ESI-MS/MS | USA |
| Keshavarz-Maleki et al. (2021) [21] | - Breast cancer mastectomy patients (n: 41); - Control group: mammoplasty patients (n: 11). |
- Cancerous patients 4.20 ± 2.40; - Control group: 1.80 ± 1.05. |
ELISA assay | Iran |
| Salamanca-Fernández et al. (2020) [70] | Sub-cohort of the Spanish European Prospective Investigation into Cancer and Nutrition (EPIC) (n: 4812): - Breast cancer cases (n: 547); - Prostate cancer cases (n: 575); - Sub-cohort participants (n: 3690). |
Geometric mean: - Breast cancer sub-cohort: 1.10; - Breast cancer cases: 1.12; - Prostate cancer sub-cohort: 1.29; - Prostate cancer cases: 1.33. |
UHPLC-MS/MS | Spain |
HPLC: high-pressure liquid chromatography; HPLC-ESI-MS/MS: high-performance liquid chromatography/electrospray ionization tandem mass spectrometry; LC-MS/MS: high-performance liquid chromatography coupled with tandem mass spectrometry; UHPLC-MS/MS: ultra-high-performance liquid chromatography with tandem mass spectrometry; ELISA: enzyme-linked immunosorbent assay.