Table 10.
Toxicity profiles of best-docked molecules.
| Sr. No. | Compound Name | Predicted LD50 (mg/kg) |
Predicted Toxicity Class | Hepatotoxicity | Carcinogenicity | Immunotoxicity | Mutagenicity | Cytotoxicity |
|---|---|---|---|---|---|---|---|---|
| 1. | Octadecanoic acid, methyl ester | 5000 | 5 | Not active | Not active | Not active | Not active | Not active |
| 2. | 4H-Pyran-4-one, 2,3- dihydro-3,5-dihydroxy-6- methyl- | 595 | 4 | Not active | Not active | Not active | Active | Not active |
| 3. | Ethyl oleate | 3000 | 5 | Not active | Not active | Not active | Not active | Not active |
| 4. | Eicosanoic acid, methyl ester | 5000 | 5 | Not active | Not active | Not active | Not active | Not active |
| 5. | 1,6-Anhydro-β-ᴅ-glucopyranose | 23,000 | 6 | Not active | Not active | Not active | Not active | Not active |
| 6. | Phthalic acid, bis(7- methyloctyl) ester | 1340 | 4 | Not active | Active | Inactive | Not active | Not active |
| 7. | Di-n-octyl phthalate | 1340 | 4 | Not active | Active | Not active | Not active | Not active |
| 8. | Phenol, 2,2′-methylenebis[6- (1, 1-dimethylethyl)-4-(1- methylpropyl) | 3430 | 5 | Not active | Not active | Not active | Not active | Not active |
| 9. | γ-Sitosterol | 890 | 4 | Not active | Not active | Active | Not active | Not active |
| 10. | Acarbose | 24,000 | 6 | Active | Not active | Active | Not active | Not active |