ANAL-2

^bFor melanoma histology, see the NCCN Guidelines for Melanoma*; for adenocarcinoma, see the NCCN Guidelines for Rectal Cancer (elsewhere in this issue).

^cCT should be with IV and oral contrast. Pelvic MRI with contrast.

^dPET/CT scan does not replace a diagnostic CT. PET/CT performed skull base to mid-thigh.

^eSee Principles of Surgery (ANAL-A†).

^fModifications to cancer treatment should not be made solely on the basis of HIV status.

^gSee Principles of Chemotherapy (ANAL-B†).

^hSee Principles of Radiation Therapy (ANAL-C†).

ⁱThe perianal region starts at the anal verge and includes the perianal skin over a 5-cm radius from the squamous mucocutaneous junction.

*To view the most recent version of these guidelines, visit NCCN.org.

†Available online, in these guidelines, at NCCN.org.