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6-shogaol administration significantly reduced pressure-overload-induced systolic dysfunction in mice. Eight weeks after surgery, cardiac function was determined by echocardiography. (A) Representative echocardiography images (M-mode) at 8 weeks after sham or TAC surgery. The X-axis represents time; the Y-axis represents distance. (B,C) Quantified values of FS and LVPWd are shown as mean ± SEM (n = 10 mice).
