Appendix 1—table 3. Prediction metrics for different diagnostic groups in the different cohorts.
| Cohorts | Correlation with age | MAE (y) | R2 | RMSE | |||
|---|---|---|---|---|---|---|---|
| R | P-value | ||||||
| CU individuals | |||||||
| ADNI | 0.575 | <0.001 | 8.153 | 0.331 | 4.953 | ||
| EPAD | 0.634 | <0.001 | 4.494 | 0.402 | 5.456 | ||
| MCI individuals | |||||||
| ADNI | 0.599 | <0.001 | 6.739 | 0.358 | 5.760 | ||
| EPAD | 0.557 | <0.001 | 5.22 | 0.311 | 5.871 | ||
The Pearson’s correlation coefficient (R) between predicted brain-age and chronological age, R2 , root mean square error (RMSE), and mean absolute error (MAE) for CU and MCI individuals from ADNI and EPAD.