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. Author manuscript; available in PMC: 2023 May 12.
Published in final edited form as: Nature. 1998 Jul 2;394(6688):82–84. doi: 10.1038/27925

Figure 4.

Figure 4

Notch activity prevents G2 arrest. a, Disc stained for Wg protein (yellow); Wg is not expressed in clones lacking Su(H) activity (arrows). b, BrdU incorporation (red) in Su(H)-deficient clones (lacking blue staining). c, CycA expression (yellow) in a Su(H)-deficient clone (inside the outline) in the ZNC. Only Su(H)-deficient cells adjacent to Wg-expressing cells (outside the clone) accumulate CycA (arrowheads). d, Overproduction of cycE in discs expressing activated Notch (NΔE) leads to BrdU incorporation (red) throughout the ZNC. e, Anti-Ac staining, showing expression outside the ZNC (red; arrows), but not where NΔE is expressed (green). Insert, magnification of two Ac-positive cells in the ZNC, showing no overlap with NΔE expression. f, Single-channel image of disc in e showing lack of ac expression in the ZNC (blue arrow; compare with Fig. 2d).