Table 3.
Suggested treatment duration for common fungal infections.
Condition | Treatment duration |
---|---|
Uncomplicated invasive candidiasis | Two weeks after the first negative blood culture [70] |
Complicated invasive candidiasis (e.g., sanctuary sites, endocarditis) | Three to 12 months, depending on clinical improvement and assessment of the local site (e.g., fundus examination, cerebrospinal fluid parameters in case of meningitis) and radiological images (magnetic resonance imaging or computed tomography etc.), if available [24,25,71] |
Pulmonary aspergillosis | Six to 12 weeks, provided there is clinical and radiological improvement [72] |
Disseminated aspergillosis | Up to 12 months, depending on the localization and possibilities of surgical removal [41,69] |
Mucormycosis | Complete surgical debridement and at least 2 weeks of amphotericin B lipid formulation, followed by posaconazole or isavuconazole for 6–12 weeks [42,73] |