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. 2023 May 12;14:2750. doi: 10.1038/s41467-023-38379-8

Table 1.

WHO classification of malaria cases3

Term Description
Imported case Malaria case or infection in which the infection was acquired outside the area in which it is diagnosed
Introduced case A case contracted locally, with strong epidemiological evidence linking it directly to a known imported case (first-generation local transmission)
Indigenous case A case contracted locally with no evidence of importation and no direct link to transmission from an imported case
Induced case A case the origin of which can be traced to a blood transfusion or other form of parenteral inoculation of the parasite but not to transmission by a natural mosquito-borne inoculation

Furthermore, WHO defines a case as the occurrence of malaria infection in a person in whom the presence of malaria parasites in the blood has been confirmed by a diagnostic test3; therefore cases are defined on infection status and not on clinical symptoms.