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. 2023 May 12;14(5):321. doi: 10.1038/s41419-023-05843-8

Fig. 3. hUC-MSCs modulated the expression of important extracellular matrix proteins in SAMP8 mice.

Fig. 3

A The representative immunohistochemical images of ECM depicted dystrophin protein expression in the SAMP8 mouse model (scale bar = 100 μm), with individual cells expressing positive protein shown under high magnification within the square (scale bar = 25 μm). The percentage of dystrophin among different groups in the visual field area was quantified (PR1 & PBS = 0.0001; PMSC & PBS = 0.0001) (C) (n = 8 or 10 views per group from 5–6 male mice). B Representative immunohistochemistry images indicated the expression of Laminin protein in SAMP8 mice (scale bar = 50 μm). The average fluorescence value of Laminin protein expression was quantified according to the random visual field in different SAMP8 mice groups (PR1 & PBS = 0.0032; PMSC & PBS = 0.0001) (D) (n = 8 or 10 views per group from 5–6 male mice; all data shown as mean ± SEM, *P < 0.05, **P < 0.01, *** P < 0.001).