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. 2023 May 12;14:2744. doi: 10.1038/s41467-023-38271-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A Cancer relevant associations by category with barplot showing the total number of genes implicated by polygenic risk scores (PRSs), polygenic survival score (PSS) and polygenic ICB score (PICS). B Mean enrichment ratio of genetic model immune microenvironment variants in 11 histone marks with corresponding enrichment ratios in 14 specific cell types. Number of cell types analyzed for each histone mark are given. C Barplot of cell-type specific TIME eQTLs implicated by DICE and ieQTL analysis. Source data are provided in the Source Data file.