Figure 1.

Aims and methods of investigating the effects of variation in P2RX7 in interaction with childhood adversities and recent life events on current anxiety: study population, quality control steps and statistical analyses. SNP single nucleotide polymorphism, HWE Hardy–Weinberg equilibrium, MR missingness rate, MAF minor allele frequency, BSI-anxiety Brief Symptom Inventory anxiety score, ADD additive model, DOM dominant model, REC recessive model, CHA childhood adversities, RLE recent life events.