Fig. 1. Porcupine plot displaying 21 genome-wide significant hits for all impulsivity facets and drug experimentation.

CADM2 was consistent across 3/8 impulsivity facets [Sensation Seeking (UPPS-P), Motor and Nonplanning impulsivity (BIS-11)] at a genome-wide association level, and with 3 more impulsivity facets [Attentional (BIS-11), Negative Urgency and Premeditation (UPPS-P]), at a gene-based level (Table S8). CADM2 was also associated with risky behavior, such as Drug Experimentation.