Table 3.

Number and percent of Deafness Variation Database missense variants belonging to each AlphaFold2 confidence range based on Deafness Variation Database classification

	Model confidence
DVD classification	< 50	50–70	70–90	> 90
B (1.4%)	719 (0.6%)	231 (0.2%)	506 (0.4%)	269 (0.2%)
LB (21.8%)	15,395 (12.0%)	3153 (2.5%)	5973 (4.7%)	3386 (2.6%)
LP (2.1%)	579 (0.5%)	203 (0.2%)	827 (0.7%)	832 (0.7%)
P (4.9%)	1201 (0.9%)	470 (0.4%)	2084 (1.6%)	2573 (2.0%)
VUS (70.1%)	25,707 (20.1%)	10,306 (8.0%)	30,106 (23.5%)	23,647 (18.5%)
Total	43,611 (34.1%)	14,393 (11.3%)	39,574 (30.9%)	30,956 (24.0%)