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. 2022 Dec 29;33(6):3984–3994. doi: 10.1007/s00330-022-09362-6

Table 3.

Model performance for predicting pCR status after neoadjuvant RT and targeted therapy in patients with STS

Model AUC 95% CI Sensitivity (%) Specificity (%) Accuracy (%)
Pre_Model 0.78 0.410~1 80 88 86.7
 Pre_T2_original_shape_Flatness
Post_Model 0.76 0.417~1 80 88 83.3
 Post_T1_original_shape_Flatness
Delta_Model 0.92 0.788~1 80 92 83.3
 Delta_T1_original_glcm_ClusterShade
 Delta_T2_original_glszm_SizeZoneNonUniformity
Combined_Model 0.95 0.874~1.000 100 84 88.7
 Pre_T2_original_shape_Flatness
 Post_T1_original_shape_Flatness
 Delta_T1_original_glcm_ClusterShade
 Delta_T2_original_glszm_SizeZoneNonUniformity
AJCC 0.52 0.305~0.743 100 16 56.7
RECIST 1.1 0.52 0.260~0.780 60 44 58.1

AUC, area under the receiver operating characteristic curve; CI, confidence interval; AJCC, American Joint Committee on Cancer; RECIST 1.1, Response Evaluation Criteria in Solid Tumors version 1.1