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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2022 Nov 21;15(3):e1870. doi: 10.1002/wnan.1870

Figure 4.

Figure 4

A – Qualitative and quantitative eGFP expression using confocal microscopy and flow cytometry indicating enhanced expression using liposome-protamine complex in DC2.4 cells (p < 0.01); B, D) Flow cytometry for estimation of enhanced CD86+ and MHC II in bone marrow derived dendritic cells; C) Antitumor efficacy in terms of change in tumor volume, body weight and tumor size in a Lewis lung cancer mice model indicating significant tumor volume reduction in the cationic liposome protamine group compared to liposome mRNA (p < 0.01), protamine mRNA (p < 0.05) and control group (p < 0.001). Reprinted with permission from Mai et al. (Mai et al., 2020). Copyright © 2020. Elsevier Ltd.