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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2022 Nov 21;15(3):e1870. doi: 10.1002/wnan.1870

Figure 6.

Figure 6

A) TEM image of TLR agonist loaded PLGA nanoparticles; B) Sustained drug release imparted by polymeric nanoparticles for 200 h compared to free drug; C, D) Enhanced cytotoxicity of loaded nanoparticles compared to free drug against peripheral blood mononuclear cells at 48 h due to enhanced intracellular accumulation; E) Flow cytometry studies of CD40, CD86, SIINFEKL peptide and CD80 on bone marrow derived dendritic cells by ovalbumin and combination with 522 loaded nanoparticles (p < 0.001) compared to control group; F) Lung metastasis and tumor inhibition on B16F10 tumor mice model. Reprinted with permission from Kim et al. (H. Kim et al., 2018). Copyright © 2018. Elsevier Ltd.