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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2022 Nov 21;15(3):e1870. doi: 10.1002/wnan.1870

Figure 7.

Figure 7

A), B) TEM images of gold and silica nanoparticles, respectively; C) Protein corona characterization via dynamic light scattering and circular dichroism spectra of gold nanoparticles on HepG2 and A2780 cells; D) Protein corona characterization via DLS and circular dichroism spectra of silica nanoparticles on HepG2 and A2780 cells; E) Interaction of protein corona of nanoparticles with DC indicated by fluorescence microscopy (A and B – Rhodamine B loaded nanoparticles without protein corona) and (C and D – Rhodamine B loaded nanoparticles with protein corona) after 24 h; (E and F - gold nanoparticles) and (G and H – gold nanoparticles with protein corona) at 2 μm (E), 1 μm (F), 500 nm (G), 100 nm (H), 2 μm (I) and 1 μm (J). Vesicular endocytic uptake in Golgi area with delayed endosome formation. F) Maturation of DC leading to enhanced CD80+, CD83+ and CD86+ at 10 and 100 ug/mL concentration of gold and silica nanoparticles versus control group (p < 0.01). Reprinted with permission from (Fogli et al., 2017). Copyright © 2017.