Table 4.

Etiology of GNB PE-BSI and AMR, according to levofloxacin prophylaxis use (group A, ASCT LEVO-group; group B, ASCT NO-LEVO-group; group C, allo-HSCT LEVO-group; group D, allo--HSCT NO-LEVO-group)

Blood cultures’ isolates characteristics	Total bacterial isolates from blood cultures
	Group A	Group B	P value	Group C	Group D	P value
GNB	0	13	-	10	58
GNB resistant to PTZ	0 (0%)	2 (15%)	-	7 (70%)	17 (29%)	.027
GNB resistant to FQs	0 (0%)	2 (15%)	-	9 (90%)	30 (52%)	.036
CR-GNB	0 (0%)	0 (0%)	-	5 (50%)	3 (5%)	.001
E coli	0 (0%)	10 (77%)	-	4 (40%)	26 (45%)
E coli ESBL-producing	0 (0%)	0 (0%)		2 (50%)	7 (27%)
E coli resistant to FQs	0 (0%)	1 (10%)		4 (100%)	15 (58%)
E coli resistant to PTZ	0 (0%)	2 (20%)		2 (50%)	6 (23%)
CR-E coli	0 (0%)	0 (0%)		0 (0%)	0 (0%)
K pneumoniae	0 (0%)	1 (8%)	-	4 (40%)	13 (22%)	.254
K pneumoniae ESBL-producing	0 (0%)	1 (100%)		0 (0%)	7 (54%)
K pneumoniae resistant to FQs	0 (0%)	1 (100%)		4 (100%)	6 (46%)
K pneumoniae resistant to PTZ	0 (0%)	0 (0%)		4 (100%)	6 (46%)
CR-K pneumoniae	0 (0%)	0 (0%)		4 (100%)	0 (0%)
Other Enterobacteriaceae∗	0 (0%)	0 (0%)	-	0 (0%)	3 (5%)	-
P aeruginosa	0 (0%)	2 (15%)	-	2 (20%)	8 (14%)	.634
P aeruginosa resistant to FQs	0 (0%)	0 (0%)		1 (50%)	4 (50%)
P aeruginosa resistant to PTZ	0 (0%)	0 (0%)		1 (50%)	3 (37%)
CR-P aeruginosa	0 (0%)	0 (0%)		1 (50%)	3 (37%)
Other GNB†	0 (0%)	0 (0%)	-	0 (0%)	8 (14%)	-

Bold values represent P values that reach statistical significance (P < 0.05). PTZ, piperacillin/tazobactam.

^∗1 Klebsiella oxytoca, 1 Enterobacter cloacae, 1 Proteus mirabilis.

^†Two Ochrobactrum anthropi, 1 Stenotrophomonas maltophilia, 1 Achromobacter xylosoxidans, 1 Campylobacter jejuni, 1 Aeromonas sobrio, 1 Capnocytophaga species, 1 Sphingomonas paucimobilis.