US-responsive hybrid microbubbles
(A) Fabrication and characterization of lipid/PLGA MBs. (i) Schematic diagram of the fabrication process of lipid/PLGA MBs. (ii) SEM image showing the porous structures on the shell. (iii) Ultrasonographs of PLGA MBs, lipid MBs, and lipid/PLGA MBs. (iv) Young’s modulus results for lipid/PLGA MBs with diverse lipid ratios showing the softened shell of lipid/PLGA MBs.
(B) Schematic diagram of the fabrication process and drug-release property of DOX-lipid/PLGA MBs.89 Copyright 2019, American Chemical Society.