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. 2023 May 13;21:322. doi: 10.1186/s12967-023-04179-3

Table 1.

Study population characteristics

Controls ME/CFS Wilcoxon-test (p-value) Controls ME/CFS Wilcoxon-test (p-value)
(78 set) (78 set)
n 49 49 NA 40 38 NA
Gender Female 41 40 NA 32 29 NA
Male 8 9 8 9
Age All 51.09 ± 11.46 50.89 ± 11.40 p = 0.95 51.16 ± 11.90 51.84 ± 10.92 p = 0.79
Female 50.94 ± 11.39 49.40 ± 11.95 p = 0.59 50.98 ± 11.93 50.08 ± 11.72 p = 0.85
Male 51.85 ± 12.58 57.52 ± 4.82 p = 0.61 51.85 ± 12.58 57.52 ± 4.82 p = 0.61
BMI All 25.44 ± 4.39 26.63 ± 4.87 p = 0.23 25.56 ± 4.53 27.22 ± 4.70 p = 0.08
Female 25.35 ± 4.62 26.47 ± 5.23 p = 0.38 25.47 ± 4.86 27.17 ± 5.18 p = 0.15
Male 25.92 ± 3.11 27.34 ± 2.86 p = 0.17 25.92 ± 3.11 27.34 ± 2.86 p = 0.17
Type of onset Acute NA 79.59% NA NA 78.95% NA
Gradual NA 20.41% NA NA 21.05% NA
Disease duration  < 3 years NA 4 NA NA 2 NA
 > 3 years NA 45 NA NA 36 NA
Season Fall 48.98% 44.90% NA 47.50% 42.11% NA
Summer 51.02% 55.10% NA 52.50% 57.89% NA
Site Miami, FL 18.37% 20.41% NA 17.50% 15.79% NA
Salt Lake City, UT 30.61% 28.57% NA 30.00% 28.95% NA
Incline Village, NV 22.45% 22.45% NA 22.50% 23.68% NA
New York, NY 28.57% 28.57% NA 30.00% 31.58% NA
MFI-20 General fatigue 7.61 ± 2.78 17.28 ± 3.70 p < 0.001 7.80 ± 2.80 17.42 ± 3.46 p < 0.001
Physical fatigue 6.71 ± 2.45 16.57 ± 3.54 p < 0.001 6.70 ± 2.38 16.82 ± 3.50 p < 0.001
Reduced activity 6.29 ± 2.47 15.47 ± 4.08 p < 0.001 6.25 ± 2.52 15.76 ± 3.93 p < 0.001
Reduced motivation 6.88 ± 2.45 12.45 ± 4.17 p < 0.001 6.95 ± 2.47 12.50 ± 4.39 p < 0.001
Mental fatigue 7.55 ± 3.29 14.8 ± 4.21 p < 0.001 7.45 ± 3.40 15.03 ± 4.28 p < 0.001
SF-36 Physical component score 55.49 ± 3.64 27.91 ± 9.68 p < 0.001 55.16 ± 3.57 27.67 ± 9.85 p < 0.001
Mental component score 54.02 ± 7.30 40.18 ± 10.74 p < 0.001 54.13 ± 5.23 40.83 ± 10.72 p < 0.001