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The hydrogen bonding schemes for antiparallel and parallel DNA duplexes. The antiparallel DNA duplexes are stabilized by Watson–Crick base pairing, while other schemes are possible for parallel duplexes. (A) Watson–Crick G:C base pair, (B) Hoogsteen G:C+ base pair, (C) Donohue G:C base pair, (D) Watson–Crick A:T base pair, (E) Hoogsteen A:T base pair, (F) Donohue A:T base pair and (G) C:C+ base pair.
