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. 2016 Apr 18;2016(4):CD009747. doi: 10.1002/14651858.CD009747.pub2

LaManca 1993.

Methods Design: randomised controlled trial
Randomisation: individual
Trial: daily oral iron versus placebo
Date of study: not stated
Participants Setting: athletics clubs in Florida, USA
Malaria endemicity: not stated
Included: healthy women aged 18 years to 35 years (mean age 28 years) with ferritin < 20 ng/mL
Excluded: not stated
Dropouts: none reported
Sample size: total: 20; intervention: 10, control: 10
Interventions Intervention: 100 mg elemental iron daily
Control: placebo
Duration: 8 weeks
Outcomes Iron indices, haemoglobin, hematocrit, exercise performance
Notes Compliance: iron 82% of tablets taken, placebo 85% of tablets taken
Conflicts of interest: not stated
Funded by: FSU President's Club fund and Sigma Xi. Tablets provided by SmithKline Laboratories
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Placebo administered
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not reported. Assessment of exercise outcomes may be influenced by knowledge of allocation
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No loss to follow‐up
Selective reporting (reporting bias) Unclear risk Not evident
Other bias Low risk Not evident