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. 2016 Apr 18;2016(4):CD009747. doi: 10.1002/14651858.CD009747.pub2

Taniguchi 1991.

Methods Design: randomised controlled trial
Randomisation: individual
Trial: daily oral iron with vitamin C plus exercise versus placebo with vitamin C and exercise versus daily oral iron with vitamin C (no exercise) versus vitamin C (no exercise)
Date of study: not stated
Participants Setting: colleges in Japan
Malaria endemicity: not stated
Included: female college students aged 18 years to 22 years (mean age not reported). Iron deficiency (ferritin < 6 ng/mL) not anaemic (haemoglobin > 120 g/L)
Excluded: not stated
Dropouts: not stated
Sample size: total: 54; intervention: 27, control: 27
Interventions Intervention: ferric ammonium citrate: 6 mg (approximately 1 mg of elemental iron ) + vitamin C ± exercise
Control: vitamin C ± exercise
Duration: 9 weeks
Outcomes Haemoglobin, iron status, exercise performance
Notes Compliance: not stated
Conflicts of interest: not stated
Funded by: not stated
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported
Allocation concealment (selection bias) Unclear risk Not reported
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Placebo (iron‐free vitamin C) administered to control participants
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not reported. May have influenced measurement of exercise outcomes
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Not indicated in report
Selective reporting (reporting bias) Low risk Not evident
Other bias Low risk Not evident