Taniguchi 1991.
Methods |
Design: randomised controlled trial Randomisation: individual Trial: daily oral iron with vitamin C plus exercise versus placebo with vitamin C and exercise versus daily oral iron with vitamin C (no exercise) versus vitamin C (no exercise) Date of study: not stated |
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Participants |
Setting: colleges in Japan Malaria endemicity: not stated Included: female college students aged 18 years to 22 years (mean age not reported). Iron deficiency (ferritin < 6 ng/mL) not anaemic (haemoglobin > 120 g/L) Excluded: not stated Dropouts: not stated Sample size: total: 54; intervention: 27, control: 27 |
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Interventions |
Intervention: ferric ammonium citrate: 6 mg (approximately 1 mg of elemental iron ) + vitamin C ± exercise Control: vitamin C ± exercise Duration: 9 weeks |
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Outcomes | Haemoglobin, iron status, exercise performance | |
Notes |
Compliance: not stated Conflicts of interest: not stated Funded by: not stated |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not reported |
Allocation concealment (selection bias) | Unclear risk | Not reported |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Placebo (iron‐free vitamin C) administered to control participants |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not reported. May have influenced measurement of exercise outcomes |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Not indicated in report |
Selective reporting (reporting bias) | Low risk | Not evident |
Other bias | Low risk | Not evident |