Fig. 6.
Distribution of immunoreaction products of BDNF in the hippocampus. BDNF protein was detected by Immunoflurecent staining in the hippocampus 2 weeks after the BMMSCs administration. (A) Nuclei staining by DAPI and primary antibody to BDNF and merge of them from each group (magnification, ×400). (B), The percentage of positive reaction in each group. BMMSCs-administered rats and control groups compared with the Meth-addicted group. ***P < 0.001 versus Meth-addicted group. ### P < 0.001 versus PBS-treated groups. Data are presented as the Mean ± SEM; Scale bar: 20μm; BDNF: brain-derived neurotrophic factor; (Control (n=8); IV-PBS (n=4); IN-PBS (n=4); Addicted (n=7); IV-BMMSC (n=8); IN-BMMSC (n=6).