Table 1.
Baseline characteristics of children suffering from acute uncomplicated malaria treated with artemether–lumefantrine or pyronaridine–artesunate in Ibadan SW Nigeria
| Characteristics | Drug group | Total | ρ-value | |
|---|---|---|---|---|
| AL | PA | |||
| Sex | ||||
| Male | 45 (50.0%) | 45 (50.0) | 90 (100) | 0.880 |
| Female | 42 (51.2%) | 40 (48.8%) | 82 (100) | |
| Age (months) | ||||
| Mean ± SD | 79.93 ± 37.16 | 82.39 ± 38.63 | 81.15 ± 39.80 | 0.671 |
| Range | 8–144 | 4–143 | 4–144 | |
| 3–11 months | 3 (3.5) | 5 (5.9) | 8 (4.7) | 0.703 |
| 12–59 months | 20 (23.0) | 21 (24.7) | 41 (23.8) | |
| ≥ 60 months | 64 (73.6) | 59 (69.4) | 123 (71.5) | |
| Weight (kg) | ||||
| Mean ± SD | 18.59 ± 6.49 | 18.67 ± 6.74 | 18.63 ± 6.59 | 0.938 |
| Range | 7.0–36.0 | 5.5–40.0 | 5.5–40 | |
| Temperature (°C) | ||||
| Mean ± SD | 37.7 ± 1.06 | 37.4 ± 1.07 | 37.6 ± 1.08 | 0.074 |
| Range | 35.1–40.2 | 35.9–39.9 | 35.1–40.2 | |
| Parasite density (/µl) | ||||
| Geomean | 32,755 | 28,211 | 30,424 | 0.815 |
| Range | 1035–758,958 | 1600–1,652,505 | 1035–1,652,505 | |
| Haematocrit (%) | ||||
| Mean ± SD | 32.14 ± 5.06 | 32.14 ± 5.48 | 32.14 ± 5.26 | 0.997 |
| Range | 18–41 | 18–48 | 18–48 | |
| Anaemic at DO | ||||
| Haematocrit < 30%) | 19 (21.8) | 21 (24.7) | 40 (23.3) | 0.396 |
| Height (cm) | ||||
| Mean ± SD | 110.65 ± 21.31 | 110.65 ± 28.90 | 110.38 ± 25.36 | 0.892 |
| Range | 18–143 | 18–186 | 18–186 | |