Table 7.
Day | Mean terminal tumor volume (mm3) | |||||
---|---|---|---|---|---|---|
GemHClBT | GemHClWT | p-valueǂ | 4NSG-SLNBT | 4NSG-SLNWT | p-value¤ | |
0 | 0 | 0 | Ns | 0 | 0 | 0 |
1 | 12.5 ± 6 | 13.9 ± 2 | ns | 12.6 ± 2 | 16 ± 3 | 0.004 |
3 | 25.0 ± 12 | 27.8 ± 4 | ns | 25.3 ± 3 | 32 ± 5 | 0.004 |
5 | 35.7 ± 18 | 39.7 ± 5 | ns | 36.2 ± 4 | 46.1 ± 9 | 0.004 |
7 | 73.0 ± 21 | 43.5 ± 16 | ns | 51.2 ± 9 | 50.7 ± 17 | ns |
9 | 229. ± 181 | 177.8 ± 60 | ns | 129 ± 35 | 182 ± 44 | 0.03 |
11 | 662. ± 198 | 583.2 ± 227 | ns | 341.4 ± 166 | 247.8 ± 76 | ns |
13 | 767. ± 194 | 646.9 ± 240 | ns | 375.6 ± 182 | 300 ± 90 | ns |
15 | 911. ± 152 | 752.6 ± 241 | ns | 418 ± 196 | 359.4 ± 108 | ns |
17 | 990. ± 151 | 850.8 ± 205 | ns | 449 ± 226 | 421 ± 112 | ns |
19 | 1129 ± 172 | 868.2 ± 294 | ns | 432 ± 105 | 494.8 ± 121 | ns |
21 | 1204 ± 184 | 1053 ± 86 | 0.05 | 429.3 ± 68 | 564.5 ± 128 | ns |
23 | 1456 ± 154 | 1344.7 ± 171 | ns | 521.7 ± 71 | 896.3 ± 93 | 0.0003 |
25 | 1681 ± 172 | 1748.2 ± 223 | ns | 1044.5 ± 40 | 1002.7 ± 96 | ns |
Data expressed in mean ± SD, n = 5