Table 3.
Blood pressure reduction (mmHg) in sham arm of included trials
| SYMPLICITY HTN-3 | Desch et al. | ReSet | RADIANCE-HTN SOLO | SPYRAL HTN-OFF MED Pivotal | SPYRAL HTN-ON MED | REDUCE HTN: REINFORCE | REQUIRE | RADIANCE-HTN TRIO | |
|---|---|---|---|---|---|---|---|---|---|
| Sham Group | |||||||||
| Reduction in Ambulatory SBP | -4.79 | -3.5 | -2.6 | -3.1 | -0.8 | -1.6 | NR | -5.7 | NR |
| Reduction in Ambulatory DBP | -3.1 | -2.1 | -2.6 | -3 | -1.0 | -1.9 | NR | -2.6 | NR |
| Reduction in Office SBP | -11.74 | NR | NR | -3.9 | -4.1 | -2.6 | -7.1 | -7.8 | -2.8 |
| Reduction in Office DBP | -4,6 | NR | NR | -1.2 | -1.8 | -1.7 | -4.8 | -3.8 | -0.7 |
Values are mmHg. DBP – Diastolic Blood Pressure; NR – Not Reported; RDN – Renal Denervation; SBP – Systolic Blood Pressure