Table 2.
Demographic, clinical, and laboratory data of the studied groups at admission before treatment
| Parameters | Citicoline group | Control group | P |
|---|---|---|---|
| GA (weeks) | 38.3 ± 1.8 | 38.1 ± 1.7 | 0.658 |
| Birth Weight (gm) | 2990 ± 670 | 2850 ± 590 | 0.331 |
| Sex (male:female) | 20:20 | 27:13 | 0.112 |
| Duration of resuscitation (min) | 11 (6–20) | 9 (5–19) | 0.068 |
| Apgare score at 10 min | 3.58 ± 1.26 | 3.60 ± 1.32 | 0.889 |
| PH (first hour) | 6.98 ± 0.11 | 7.01 ± 0.10 | 0.305 |
| HCO3 | 12 (2–19) | 12.5 (2–20) | 0.012 |
| Base deficit | 16.13 ± 1.04 | 16 ± 0.93 | 0.679 |
| Urinary Lactate/creatine ratio | 0.79 ± 0.09 | 0.80 ± 0.09 | 0.468 |
| Sarnat staging: N (%) | |||
| -stage 2 | 19 (47.5%) | 23 (57.5%) | 0.370 |
| -stage 3 | 21 (52.5%) | 17(42.5%) | |
| EEG: N (%) | |||
| -Normal continuous | 22 (55%) | 28 (70%) | 0.554 |
| -Low voltage | 5 (12.5%) | 2 (5%) | |
| -Burst suppression | 5 (12.5%) | 4 (10%) | |
| -Seizure activity | 7 (17.5%) | 4 (10%) | |
| -Paroxysmal generalized epileptiform | 1 (2.5%) | 2 (5%) | |
GA gestational age, HCO3 bicarbonate, EEG electroencephalogram