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. 2023 May 13;27:45. doi: 10.1186/s40824-023-00388-5

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — A Fabrication of the hydrogel with boronate affinity via imprinting of SMMC-7721 cells for the capture and release of tumor cells. B Microscopy images of surface morphology of the imprinted hydrogel with fixed cells. C Cryo-scanning electron microscopy (SEM) of the nanostructures inside the imprinted hydrogel. D Schematic of the principle and procedure of controllable oriented surface imprinting of boronate affinity-anchored epitopes. E Transmission electron microscopy (TEM) image of the imprinting layer of silver NPs (AgNPs) imprinted with 60 min polymerization time. A, B, C Reproduced with permission from [71], published by Wiley 2020. D, E Reproduced with permission from [77], published by The Royal Society of Chemistry 2019