. 2023 May 9;16:1735–1746. doi: 10.2147/IJGM.S405225

Table 1.

Clinical Demographics and Characteristics

Demographics	Overall	Non-Anxiety	Anxiety Disorder	p value
Participants, n	56	39	17
Age, years, mean ± SD	55.3±4.2	54.4±4.5	56.7±4.3	0.075^a
Gender, n (%)
Male	4	3	1	0.809^b
Female	52	36	16
BMI, mean ± SD	22.7±1.5	23.0±1.2	22.6±2.0	0.181^a
Education, years, mean ± SD	8.2±2.4	8.5±2.3	7.8±2.4	0.014^a
Smoking, n (%)
Current	9	5	4	0.575^b
Prior	1	1	0
Never	42	29	13
Periodic exercise, mean ± SD	1.7±0.9	1.7±1.0	1.5±1.0	0.585^a
Sleep time, mean ± SD	6.6±0.7	6.6±0.7	6.5±0.7	0.818^a
Family history, n (%)	5	2	3	0.131^b
Disease duration, years, mean ± SD	8.5±4.5	8.1±4.8	8.8±2.6	0.017^a
Other systemic disease, n (%)	11	6	5	0.224^b
Ophthalmic medical survey
Contact lens	27	18	9	0.602^b
Ophthalmic surgery	2	1	1	0.538^b
ESSDAI score	7.2±2.1	6.7±1.8	8.0±2.2	0.022^a
ESSPRI score	6.5±1.0	6.4±1.0	6.8±1.0	0.176^a
OSDI score category
0–12	0	0	0	0.032^b
13–22	13	10	3
23–32	21	18	3
33–100	22	11	11
Anxious state (STAI-S)
Non-case	50	39	11	<0.001^b
Case	6	0	6
Laboratory test
RF positive	28	20	8	0.512^b
C3	1.05±0.1	1.03±0.1	1.05±0.1	0.605^a
C4	0.16±0.03	0.16±0.02	0.17±0.03	0.082^a
IgG	13.8±2.1	13.8±2.5	13.9±1.8	0.789^a
ANA positive	41	29	12	0.77^b
Anti-SSA positive	42	30	12	0.615^b
Anti-SSB positive	25	18	7	0.17^b

Notes: ^amann–Whitney U-test. ^bChi-square test.