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. 2023 May 9;16:2861–2882. doi: 10.2147/IDR.S406243

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© 2023 Mao et al.

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Optimization of the detection method for the signaling molecule AI-2. (A) The optimization of the optimal detection conditions of AI-2. (B) The relationship between AI-2 activity and density value in strain wld10. (C) The comparison of fluorescence intensity of AI-2 in each strain. (D) The expression level of luxS gene in each strain, which is responsible for the high-yielding AI-2 signal, in S. aureus. The alphabets a, b, c, and d indicate differences between groups, while the same alphabet indicate little to no variation between samples. If the samples have different alphabet, there is a significant difference between them (P< 0.05).