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. Author manuscript; available in PMC: 2024 Feb 2.
Published in final edited form as: Mol Cell. 2023 Feb 2;83(3):343–351. doi: 10.1016/j.molcel.2023.01.005

Figure 1. Proposed functions and effector proteins for 6mA on mammalian genomic DNA and mtDNA.

Figure 1.

The downward and upward arrows refer to the repression or upregulation of transcription, respectively. The question marks refer to the putative 6mA methylases, demethylases, and binding proteins but with conflicting data or a lack of strong evidence.