Table 1.
Baseline Participant Characteristics Stratified by Study
| T1DM (n=50) | Controls (n=20) | p-value | |
|---|---|---|---|
| Age (years) | 16.0 ± 3.0 | 16.1 ± 2.9 | 0.94 |
| Tanner stage | 5 (4-5) | 5 (4-5) | 0.99 |
| T1DM duration (years) | 5.7 ± 2.6 | -- | -- |
| Sex (female, %) | 50% | 70% | 0.13 |
| Race/ethnicity (%) | |||
| Black non-Hispanic | 2 | 5 | 0.41 |
| Hispanic | 6 | 0 | |
| White non-Hispanic | 92 | 95 | |
| BMI (kg/m2) | 23.4 ± 5.1 | 22.7 ± 3.7 | 0.58 |
| Weight (kg) | 67.5 ± 17.6 | 62.7 ± 14.5 | 0.28 |
| Fat mass (kg) | 20.3 ± 9.4 | 19.2 ± 6.7 | 0.62 |
| Blood pressure (mm Hg) | |||
| Systolic blood pressure | 119 ± 9 | 117 ± 8 | 0.30 |
| Diastolic blood pressure | 74 ± 11 | 73 ± 11 | 0.89 |
| Mean arterial pressure | 89 ± 9 | 88 ± 9 | 0.66 |
| UACR (mg/g) | 6 (5–14) | 7 (4–10) | 0.87 |
| GFR (ml/min) | 189 ± 40 | 136 ± 22 | <0.0001 |
| GFR (ml/min/1.73m2) | 183 ± 26 | 139 ± 8 | <0.0001 |
| RPF (ml/min) | 820 ± 125 | 615 ± 65 | <0.0001 |
| RPF (ml/min/1.73m2) | 824 ± 120 | 634 ± 85 | <0.0001 |
| HbA1c (%) | 8.7 ± 1.3 | 5.2 ± 0.2 | <0.0001 |
| LDL-C (mg/dL) | 89 ± 24 | 92 ± 24 | 0.65 |
| HDL-C (mg/dL) | 51 ± 10 | 46 ± 9 | 0.08 |
| Triglycerides (mg/dL) | 78 ± 35 | 88 ± 36 | 0.27 |
Data are presented as mean ± SD, median (IQR), or percent.
Abbreviations: BMI, body mass index; GFR, glomerular filtration rate; GIR, glucose infusion rate; HDL-C, high-density lipoprotein cholesterol; HbA1c, hemoglobin A1c; LDL-C, low-density lipoprotein cholesterol; RPF, renal plasma flow; T1DM, type 1 diabetes mellitus; UACR, urinary albumin/creatinine ratio.
Of note similar table was published in Diabetes for a separate analysis