Table 3.
Comparison of clinical performance characteristics vs previous studies
Parameter | MATLOC | DOCUMENT | This Study |
---|---|---|---|
Number of subjects | 483 | 320 | 211 |
Sensitivity (95% CI) | 68% (57%−77%) | 62% (52%−72%) | 74% (63%−83%) |
Specificity (95% CI) | 64% (59%−69%) | 64% (57%−70%) | 60% (51%−69%) |
DOCUMENT, Detection of Cancer Using Methylation Events in Negative Tissue; MATLOC, Methylation Analysis to Locate Occult Cancers.