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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: J Biomol Struct Dyn. 2022 Nov 14;41(19):9745–9755. doi: 10.1080/07391102.2022.2146197

Figure 2.

Figure 2.

(A) Interactions of W320 and R346 with P295, R366 and R367 in a third molecule at the hexameric interface. (B)Conformational differences of the essential catalytic residue R400 (shown in stick) in the structures of WT hHsp90αMC (orange) and hHsp90αMC_W320A (green). (C) Interactions of R620 with residues N397 and I398 on the catalytic loops in WT hHsp90αMC hexamer structure.