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. 2023 May 10;16:529–540. doi: 10.2147/JAA.S405929

Table 1.

Study Characteristics

Authors/Year Region/Country Study Type Population (Number) Average Age (Years Old) Daily Mean Concentration of PM2.5 (μg/m3) Lag (Days) Outcome: Observed Change (Change per 10 μg/m3 PM2.5 Increase in Pollutant When Applicable) Statistical Model
Lu Ma/200822 Yotsukaido, Japan Cohort study Children with severe asthma (19) Mean age 12.9 22.6 Lag0–1 PEF:-3.40L/min (95% CI:-6.47, −0.33) Generalized Estimating Equation model
BingYu /201023 Taiwan,China Cohort study Healthy, asthmatic, and allergic rhinitis school children (100) Mean age 10.6 28.2 Lag0–1 FVC:-0.16L (95% CI:-0.23, −0.08)
FEV1:-0.12L (95% CI:-0.20, −0.05)
Mixed-effects models
Yamazak /201124 Yotsukaido, Japan Cohort study Children with severe asthma (17) 8–15 24 Lag0–1 PEF:-2.96L/min (95% CI:-4.55, −1.37) Generalized Estimating Equations
Ludmilla/201225 Amazon,Brazilian Cohort study Healthy and asthmatic children (280) Mean age 10.4 24.34 Lag0–1 PEF:-0.29L/min (95% CI:-0.52, −0.07) Mixed-effects models
Ludmilla/201426 Tangara,Brazil Cohort study Healthy and asthmatic children (220) Mean age 10.3 19.6 Lag0–4 PEF:-0.54L/min (95% CI:-0.946, −0.137) Mixed-effects models
Masanari/201627 Matsue,Japan Cohort study Healthy,asthmatic,allergic rhinitis children (339) 10–12 23 Lag0–1 PEF:-1.72 L/min (95% CI:-3.82, 0.36) Linear mixed model
Dandan Xu/201828 Nanjing, China Cohort study Healthy School children (86) Mean age 9 84.3 Lag0–1 PEF:-1.76L/min (95% CI: −3.549, 0.024)
FVC: −0.023L (95% CI: −0.033, −0.013)
FEV1:-0.019 L (95% CI: −0.029, −0.009)
Mixed-effects regression mode
Liu Weiyan/201910 Hangzhou,China Cohort study Healthy school children (1685) Mean age 9.8 50 Lag0–1 PEF:-2.34L/min (95% CI:-4.02, −0.72) Linear mixed model
Dandan Xu/202029 Zhejiang, China. Cohort study Healthy and asthmatic school children (848) Mean age 9.7 67.58 Lag 1 PEF:-4.02L/min (95% CI: −5.36, −2.73)
FVC:-0.034L (95% CI: −0.045, −0.023)
FEV1:-0.033L (95% CI: −0.044, −0.021)
Mixed-effects regression mode
Yang Xiaoyan/202011 Beijing, China Cohort study Healthy school children (51) 9–12 57.75 Lag4 PEF:-0.49L/min (95% CI:-2.84, 1.87)
FVC:-0.033L (95% CI:-0.050, −0.015)
FEV1:0.003L (95% CI:−0.015, 0.020)
Linear mixed effects model
WU Xingbin/202030 Jinan, China Cohort study Healthy school children (484) Not reported 90 Lag0–1 PEF:-1.54L/min (95% CI:-2.33, −0.76)
FVC: −0.008L (95% CI:-0.014, −0.003)
FEV1:-0.008L (95% CI:-0.012,-0.003)
Multiple linear regression model

Abbreviations: PEF, peak expiratory flow; FVC, forced vital capacity; FEV1, the forced expiratory volume in one second; CI, confidence interval.