Fig. 2.

Plant-derived flavonol-containing foods have shown profound medicinal activity against disease and maintaining a healthy diet. Quercetin is found to be useful in homeostasis and as a modulator of controlled blood sugar levels in the body. Associate transporters and organs with enzymatic activity are regulated by quercetin, which controls the organ systems by either increasing or decreasing enzymatic activity, enzyme secretion, and expression of transporters, signaling pathways, and other aspects. It controls ROS (Reactive oxygen species) production in the absence of glucose in the pancreatic cell. Besides, quercetin also alleviates glucose assimilation via the GLUT2 receptor. Kaempferol (KMF) is observed in the anti-inflammatory response of cells against pathogen-mediated inflammation. Inflammation is a natural phenomenon that protects the host from damage by pathogens. Uncontrolled inflammation generates a cytokine storm that leads to potential damage to cells. Kaempferol inhibits many inflammatory signal transduction pathways at various levels (i.e., NF-kB, JAK-STAT pathway) NF-kB = Nuclear Factor kB