Table 6:
Efficacy of produced antiparasitic drugs in combating equine parascarosis
| Experiment number / group of animals | Test product | Dose (mg of active substance /kg BW) | Number of horses in group | % infected | EPGa mean | EEb % | IEc % | Efd % | P value e |
|---|---|---|---|---|---|---|---|---|---|
| 1 / Control | Placebo | – | 10 | 30.0 |
12.3±6.5*** 1.53±0.15 |
– | – | – | – |
| 1 / Treatment | PPIA-1g | 0.2 IVMh 10.0 ALBi |
10 | 0.0 |
0 0 |
100 | 100 | 100 | NA |
| 2 / Control | Placebo | – | 20 | 35.0 |
23.3±8.2 1.77±0.09 |
– | – | – | – |
| 2 / Treatment | PPIANk | 0.2 IVM 10.0 ALB 10.0 NSl |
16 | 0.0 |
0 0 |
100 | 100 | 100 | NA |
| 3 / Control | Placebo | – | 12 | 25.0 |
7.9±4.5 1.46±0.08 |
– | – | – | – |
| 3 / Treatment | PPIA-2-1m | 0.2 IVM 10.0 ALB |
14 | 14.3 |
0.68±0.5 0.67±0.05 |
42.8 | 91.4 | 54.1 | < 0.05 |
| 3 / Treatment | PPIA-2-3n | 0.2 IVM 3.0 ALB |
13 | 0.0 |
0 0 |
100 | 100 | 100 | NA |
| 3 / Treatment | PPIA-2-5o | 0.2 IVM 5.0 ALB |
11 | 0.0 |
0 0 |
100 | 100 | 100 | NA |
| 3 / Treatment | PPI-initialp | 0.2 IVM | 12 | 16.6 |
2.9±2.4 1.12±0.2 |
33.6 | 63.3 | 23.3 | > 0.05 |
| 3 / Treatment | PPA-initialq | 10.0 ALB | 10 | 20.0 |
0.73±0.6 0.85±0.03 |
20.0 | 90.8 | 41.8 | < 0.05 |
a-q
For the abbreviations see footnotes of Table 5