Table 4.
Univariate and multivariate logistic regression analysis for risk factors of HBV reactivation.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| OR(95%CI) | P | OR(95%CI) | P | |
| Age (≥60years) | 1.150 (0.342-3.864) | .821 | ||
| Gender (male) | 1.010 (0.117-8.742) | .993 | ||
| History of alcoholism (yes) | 2.343 (0.684-8.031) | .176 | ||
| Antiviral prophylaxis (yes) | 0.088 (0.024-0.327) | <.001 | 0.047 (0.008-0.273) | .001 |
| HBsAg (+) | 0.194 (0.032-1.195) | .077 | 2.144 (0.217-21.210) | .514 |
| HBeAg (+) | 1.446 (0.285-7.345) | .656 | ||
| HBV DNA (detectable) |
0.083 (0.010-0.664) | .019 | 0.073 (0.007-0.727) | .026 |
| ALT, U/L | 1.007 (0.985-1.029) | .538 | ||
| ALT >1 ULN | 1.121 (0.315-3.986) | .860 | ||
| TBil | 1.015 (0.969-1.063) | .523 | ||
| ALB | 1.067 (0.942-1.209) | .308 | ||
| Child-pugh (B) | 1.446 (0.285-7.346) | .656 | ||
| BCLC (C) | 0.838 (0.237-2.960) | .783 | ||
| AFP (≥200 ng/ml) | 1.426 (0.426-4.777) | .565 | ||
| WBC | 0.972 (0.806-1.171) | .764 | ||
| NLR (>2.5) | 0.347 (0.103-1.172) | .088 | 0.215 (0.044-1.053) | .058 |
| PLT | 1.005 (0.999-1.012) | .113 | ||
AFP, alpha fetoprotein; ALB, albumin; ALT, alanine aminotransferase; BCLC, Barcelona Clinic Liver Cancer; CI, confidence intervals; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; NLR, neutrophil to lymphocyte ratio; OR, odds ratio; TBil, total bilirubin; WBC, leukocyte; ULN, upper limit of normal; PLT, platelet.