Table 2.
Current recommendations for colorectal cancer surveillance from different national and international organisations.
| Country/Continent of origin | Organisation | Age to start surveillance (with corresponding pathological MMR gene mutation, where applicable) | Surveillance interval (with corresponding MMR gene mutation, where applicable) | Comments |
|---|---|---|---|---|
| Australia | Cancer Institute of New South Wales (34) | 25 years (MLH1/MSH2)
35 years (MSH6/PMS2) |
1-2 years | Review all cases at age 60 years with a view to reducing frequency |
| Europe | Mallorca Guidelines from The European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP) (35) | 25 years (MLH1/MSH2)
35 years (MSH6/PMS2) |
2-3 years (MLH1/MSH2/MSH6)
5 years (PSM2) |
|
| European Society of Gastrointestinal Endoscopy (ESGE) Guideline (36) | 25 years (MLH1/MSH2)
35 years (MSH6/PMS2) |
2 years | ||
| European Society of Medicine (ESMO) (37) | 25 years (MLH1/MSH2)
35 years (MSH6/PMS2) |
1-2 years | Offer colonoscopy 5 years younger than age of youngest diagnosed CRC case in family (if diagnosed before age 25) | |
| France | French National Authority for Health (38) | 25 years | 2 years | Offer colonoscopy 5 years younger than age of youngest diagnosed CRC case in family (if diagnosed before age 25) |
| Germany | German Consortium for Familial Colorectal Cancer (39) | 25 years | 1-2 years | |
| Japan | Japanese Society for Cancer of the Colon and Rectum (JSCCR) (40) | 20-25 years | 1-2 years | |
| Netherlands | Integrated Cancer Centre Netherlands (41) | 25 years | 2 years | |
| Spain | Spanish Society of Medical Oncology (SEOM) (42) | 20-25 years | 1-2 years | Offer colonoscopy 2-5 years younger than age of youngest diagnosed CRC case in family (if diagnosed before age 25) |
| UK | British Society of Gastroenterology BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG) (10) | 25 years (MLH1/MSH2) 35 years (MSH6/PMS2) |
2 years | Until age 75 years |
| USA | US Multi-Society Task Force (USMSTF) (43) | 20-25 years (MLH1/MSH2)
30 years (MSH6) 35 years (PMS2) |
1 year | Offer colonoscopy 2-5 years younger than age of youngest diagnosed CRC case in family (if diagnosed before age 25) |
| American College of Gastroenterology (ACG) (3) | 20-25 years (MLH1/MSH2)
25-30 years (MSH6/PMS2) |
1-2 years | ||
| American Society of Clinical Oncology (ASCO) (44) 1 | 25 years (MLH1/MSH2)
35 years (MSH6/PMS2) |
1-2 years | Offer colonoscopy 5 years younger than age of youngest diagnosed CRC case in family (if diagnosed before age 25) | |
| National Comprehensive Cancer Network (NCCN) (45) | 20-25 years (MLH1/MSH2) 30-35 years (MSH6/PMS2) |
1-2 years 1-3 years |
Offer colonoscopy 2-5 years younger than age of youngest diagnosed CRC case in family (if diagnosed before age 25) |