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. 2023 May 1;14:1192940. doi: 10.3389/fimmu.2023.1192940

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Copyright © 2023 Sun, Li, A, Li, Zhong, Chen, Liu, Zhang, Zhu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MP altered mRNA expression profile of Aβ_1-42-induced mice. (A) Schematics of the experimental design. (B) Heatmap of DGEs in MP-treated Aβ_1-42-induced mice and the control Aβ_1-42-induced mice. (C) KEGG annotation for the differentially expressed genes. (D) GO enrichment analysis of DEGs and functional analysis for genes. (E) Hub genes identified from the PPI network based on the MCC algorithm in cytoHubba. (F) Quantified image shows the mRNA expression level of genes associated with synaptic function. (G) Quantified image shows the mRNA expression level of genes associated with immune response. Data are shown as mean ± SEM (n = 3). ^#P < 0.05 vs. Aβ_1-42-induced group.