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. 2023 May 1;13:1166839. doi: 10.3389/fcimb.2023.1166839

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Copyright © 2023 Hurtado-Tamayo, Requena-Platek, Enjuanes, Bello-Perez and Sola

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genetic organization of the genome 3’ end in highly pathogenic human CoVs. Structural and accessory genes are shown. Gray boxes indicate structural genes: spike (S), envelope (E), membrane (M) and nucleocapsid (N). Accessory genes are represented in different colors. Their names are indicated as numbers above or below the boxes. Sequence conservation of accessory genes is indicated with the same color. The Poly A sequence (An) is represented at the 3´end of each CoV genome. Created with BioRender.com.